EPOETIN
(Eprex, Erythropoetin, Epoetin alfa, EPO)Standard Prescription
epoetin__units IV/SC__(frequency) (__units/kg/week) or (__units/kg/dose)
Note: Please specify day(s) of the week administered.
Note: Please specify day(s) of the week administered.
Dosages
Anemia in chronic kidney disease:
Infants, Children and Adolescents
50-150 units /kg/week SC/IV or divided 2-3 times weekly
Titrate dose to achieve target Hgb
Infants, Children and Adolescents
50-150 units /kg/week SC/IV or divided 2-3 times weekly
Titrate dose to achieve target Hgb
Pre-operative use to decrease blood product exposure*
300 units/kg/week SC x 3-4 weeks Mechanism of Action
Colony-stimulating factor. Human erythropoietin produced in cell culture using recombinant DNA technology.
Forms Supplied
Prefilled syringes, single use, preservative-free:
2,000 units
3,000 units
4,000 units
6,000 units
10,000 units
2,000 units
3,000 units
4,000 units
6,000 units
10,000 units
Comments
Do not shake or transport via pneumatic tube system. Shaking may denature proteins and render the product inactive.
SC route provides sustained serum levels and longer half life compared to IV route.
IV use restricted to hemodialysis patients only.
*Consult hematology for this indication (pre-op use) at least 4 weeks prior to surgery date.
SC route provides sustained serum levels and longer half life compared to IV route.
IV use restricted to hemodialysis patients only.
*Consult hematology for this indication (pre-op use) at least 4 weeks prior to surgery date.
References
32, 44, 77
Last Edited
2022-06-22 23:46:58