MEROPENEM
(Merrem)Standard Prescription
meropenem__mg IV Q__H (__mg/kg/24hr)
Dosages
Children:
Urinary Tract Infection: 10 mg/kg/dose IV Q8H
Urinary Tract Infection: 10 mg/kg/dose IV Q8H
Moderate to Severe Infections:
20 mg/kg/dose IV Q8H
20 mg/kg/dose IV Q8H
Febrile Neutropenia:
20 mg/kg/dose IV Q8H. Maximum: 1000mg/dose
20 mg/kg/dose IV Q8H. Maximum: 1000mg/dose
Cystic Fibrosis:
40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose
40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose
Meningitis:
40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose
40 mg/kg/dose IV Q8H. Maximum: 2000 mg/dose
Mechanism of Action
Carbapenem antibiotic
Forms Supplied
Injection: 500 mg vial; 1 g vial
Comments
Doses require adjustment if creatinine clearance is < 50 mL/min.
Less nausea and vomiting, decreased risk of seizures compared to imipenem.
Less nausea and vomiting, decreased risk of seizures compared to imipenem.
References
6, 44, 213, 627
Last Edited
2022-07-06 23:06:18