PRAZOCIN

(Minipress)

Standard Prescription

prazosin __mcg PO Q__H (__mcg/kg/24 hr)

Dosages

Children:
Maintenance: 0.02-0.05 mg/kg/dose PO Q8-12H.
Maximum: 0.5 mg/kg/day or 20 mg/day

Adults:
2-20 mg/24 hr div BID-TID.
maximum 20 mg per day.

Mechanism of Action

Alpha-1-adrenergic receptor blocker.

Forms Supplied

tablets: 1 mg, 2 mg.

liquid (BCCH): 0.1 mg/mL.

Comments

Not recommended as first-line therapy for hypertension, unless specific indication for alpha-blockade.

Orthostatic hypotension may occur after initial dose. Give first dose with patient supine and consider additional monitoring.

May cause syncope, tachycardia, hypotension, dizziness, nausea, headache, drowsiness, fatigue, anticholinergic effects.

References

29, 32, 44

Last Edited

2022-09-08 05:04:16