AZITHROMYCIN
(Zithromax)Standard Prescription
azithromycin __mg PO{IV} daily x __ days (__mg/kg/24hr)
azithromycin __mg PO x 1 dose day 1, then __mg PO daily days 2 to__
azithromycin __mg PO x 1 dose day 1, then __mg PO daily days 2 to__
Dosages
Children:
PO:
Days 2 to 5: 5 mg/kg/dose PO daily
Infants >= 6 months:
Day 1: 10 mg/kg/dose PO x 1 dose
25-40 kg: 250 mg PO daily 3x/week (Mon/Wed/Fri)
Cystic Fibrosis for Nontuberculous Mycobacteria:
10-12 mg/kg/dose PO once daily (Max: 500 mg/dose)
Days 2 to 5: 250 mg PO/dose daily
PO:
Pneumonia:
Day 1: 10 mg/kg/dose PO x 1 doseDays 2 to 5: 5 mg/kg/dose PO daily
Pertussis:
Infants 1-5 months: 10 mg/kg/dose PO daily x 5 daysInfants >= 6 months:
Day 1: 10 mg/kg/dose PO x 1 dose
Days 2 to 5: 5 mg/kg/dose PO daily
IV:
10mg/kg/dose IV daily (max: 500 mg/dose)Cystic Fibrosis for Anti-inflammatory:
Less than 25 kg: 10 mg/kg/dose PO daily 3x/week (Mon/Wed/Fri) 25-40 kg: 250 mg PO daily 3x/week (Mon/Wed/Fri)
40 kg or greater: 500 mg PO daily 3x/week (Mon/Wed/Fri)
10-12 mg/kg/dose PO once daily (Max: 500 mg/dose)
Adults:
Day 1: 500 mg PO/dose x 1 doseDays 2 to 5: 250 mg PO/dose daily
Mechanism of Action
Macrolide antibiotic
Forms Supplied
Tablet: 250 mg
Suspension: 40 mg/mL
Injection: 500 mg/vial
Suspension: 40 mg/mL
Injection: 500 mg/vial
Comments
Suspension may be administered via enteral tube
Less risk for drug interactions compared to other macrolide antibiotics
IV azithromycin is comparable in cost to IV erythromycin and is simpler to administer (once daily dosing, less vein irritation).
Rare side effect: tinnutis
Less risk for drug interactions compared to other macrolide antibiotics
IV azithromycin is comparable in cost to IV erythromycin and is simpler to administer (once daily dosing, less vein irritation).
Rare side effect: tinnutis
References
6, 44, 73, 92, 303, 608, 610
Last Edited
2022-06-09 05:03:40